Michelia champaca L. Derived Phytochemicals against Peptidase Do of Bordetella pertussis Causing Cough

Phytochemicals from Michelia champaca L. plant extract are traditionally used to cure cough. Cough can be caused by many reasons. Caugh can be caused by the infection of Bordetella pertussis. The objective of the study is to identify the phytochemical of Michelia champaca capable of curing cough. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that magnoflorine can effectively deactivate the peptidase Do enzyme which will interrupt the life cycle of the microorganism and inhibit the multiplication

Beet Root Derived Phytochemicals against Escherichia coli Causing Diarrhea

Phytochemicals from Beet Root (Beta vulgaris) plant extract are traditionally used to cure Diarrhea. It is caused by Escherichia coli. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that caffeic acid can effectively deactivate the Shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism

Pavonia odorata Derived Phytochemicals against Entamoeba histolytica Causing Dysentery

Phytochemicals from Pavonia odorata plant extract are traditionally used to cure Dysentery. It is caused by Entamoeba histolytica. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that palmitic acid can effectively deactivate the Alcohol dehydrogenase enzyme thereby interrupting the life cycle of the organism

Trigonella foenum-graecum Derived Phytochemicals against Tuberculosis

Phytochemicals from Trigonella foenum-graecum plant extract are traditionally used to cure Tuberculosis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that this plant extract can effectively deactivate the dihydrofolate reductase enzyme thereby interrupting the life cycle of the organism

Vaccinium corymbosum L. Derived Phytochemicals against Diarrhea

Phytochemicals from Vaccinium corymbosum L.plant extract are traditionally used to cure diarrhea. It is caused by Escherichia coli. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that cafferic acid can effectively deactivate the shikimate dehydrogenase thereby interrupting the life cycle of the organism

Bixa orellana L. Derived Phytochemicals against Alcohol Dehydrogenase of Escherichia coli

Phytochemicals from Bixa orellana L.plant extract are traditionally used to cure Jaundice. It is caused by Escherichia coli. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that benzoic acid can effectively deactivate the alcohol dehydrogenase enzyme thereby interrupting the life cycle of the organism

Budleja asiatica Derived Phytochemicals against Eye Disease

The secondary metabolites in the plants are used for curing various diseases. The phytochemicals present in Budleja asiaticaplant extract are traditionally used to cure Eye disease. It is caused by Haemophilus influenza, whichis a facultatively anaerobic, gram-negative pathogenic bacteria. For analysis of ligand-protein interaction, the molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that lignoceric acid can effectively deactivate Aspararte semialdehyde dehydrogenase enzyme which is important macromolecule for the regulation of amino acid biosynthesis resulting in interrupting the life cycle of the microorganism

Coffea arabica L. Derived Phytochemicals against Haemophilus influenza Causing Conjunctivitis

Phytochemicals from Coffea arabica plant extract are traditionally used to cure conjunctivitis. It is caused by Haemophilus influenza. Molecular docking method applied using “Biovia DiscoveryStudio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that caffeine and chlorogenic acid can efficiently deactivate the shikimate dehydrogenase enzyme which will result in interruption of the life cycle of the microorganism

Capsicum anum L. Derived Phytochemicals against Haemophilus influenzae Causing Bronchitis

Phytochemicals from Capsicum anum L. plant extract are traditionally used to cure bronchitis. Bronchitis is caused by Haemophilus influenzae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that myrcetin and quercetin can effectively deactivate the Palmitoyl-CoA hydrolase enzyme thereby interrupting the life cycle of aemophilus influenza

Murraya koenigii Derived Phytochemicals against Dysentery

Phytochemicals are any of various biologically active compounds found in plants. These are produced by plants and have biological activity. It has been reported that Murraya koenigii leaf extract is traditionally used to cure dysentery. Dysentery is an intestinal inflammation, primarily of the colon. It can lead to mild or severe stomach cramps and severe diarrhoea with mucus or blood in the faeces. It is the infection in the intestinal tract. One enzyme, which is involved in its biochemical pathway, is known as alcohol dehydrogenase (which have pdb id.1Y9A). The molecular docking was studied by biovia discovery studio. In which the interaction is done between the phytochemical of the plant with the enzyme. The stability of the interaction was evaluated based on –CDocker energy and –CDocker interaction energy.

Trigonella foenum-graecum Derived Phytochemicals against Cough

Phytochemicals from Trigonella foenum-graecum plant extract are traditionally used to cure Cough.There are many reasons for cough. It has been reported that cough can be caused as a result of Bordetella sp. infection. The objective of the study is to identify the phytochemical of Trigonella foenum-graecum capable of curing Cough. Molecular docking method applied using “Biovia Discovery Studio”. The research clearly indicates that choline, arginine, and gentianine cannot effectively deactivate the enzyme histidinekinase of the microbe. On the other hand, carpaine and diosgenin failed to deactivate the enzyme. Thus, none of these phytochemicals can effectively deactivate the histidinekinase enzyme of Bordetella sp. and thus cannot be used to treat cough caused by this particular microbe

Trigonella foenum-graecum Derived Phytochemicals against Cellulitis

Cellulitis is a common and sometimes painful bacterial skin infection. Trigonella foenum-graecumextract is traditionally used to cure diseases like cellulitis. Phytochemicals from Trigonella foenum-graecum plant extract can cure Cellulitis. The objective of the study is to identify the phytochemical of Trigonella foenum-graecum capable of curing Cellulitis. Molecular docking method applied using “Biovia Discovery Studio”. “The experiment shows that the phytochemical sarginine, carpaine, choline, gentianine and diosgenin failed to deactivate the UDP-glucose 6-dehydrogenase enzyme of Streptococcus pyogenes for treating Cellulitis

Michelia champaca Derived Phytochemicals against Skin Disease

Phytochemicals from Michelia champaca plant extract can cure skin disease. Skin disease can becaused by many reasons. Infections due to Staphylococcus aureus is one of the main reasons for skin disease. This objective of the study is to identify the phytochemical of Michelia champaca capable of curing skin diseases. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Magnoflorine can effectively deactivate thymidylate synthase thereby interrupting the life cycle of the organism

Cardamom Derived Phytochemicals against Bronchitis Caused by Streptococcus pneumoniae

Phytochemicals from Cardamom plant extract can cure Bronchitis. One of the causes of Bronchitis is an infection of Streptococcus pneumoniae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 4-terpineol can effectively deactivate thymidine phosphorylase enzyme thereby interrupting the life cycle of the organism.

Cardamom Derived Phytochemicals against Mycoplasma pneumonia Causing Bronchitis

Bronchitis is inflammation of the bronchi in the lungs. Bronchitis is mainly caused by a viral infection and a small number of cases are caused by a bacterial infection like Mycoplasma pneumonia.Cardamom extract is a traditional medicine that is used to treat Bronchitis. The objective of the study is to identify the phytochemical of Cardamom capable of curing pneumonia-like bronchitis Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that acetic acid can effectively deactivate glycerophosphodiester phospho diesterase enzyme thereby interrupting the life cycle of the organism

Cardamom Derived Phytochemicals against Mycobacterium tuberculosis Causing Tuberculosis

Tuberculosis is a disease caused by severe infections by Mycobacterium tuberculosis, a pathogenic bacteria. These bacteria cause infections in humans and thus lead to an unhealthy life. Phytochemicals from cardamom plant extract are traditionally used to cure Tuberculosis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that acetic acid can effectively deactivate histidinol dehydrogenase (H37Rv) thereby interrupting the life cycle of the organism

Capsicum Derived Phytochemicals against Shikimate Dehydrogenase of Haemophilus influenza causing Bronchitis

Phytochemicals from Capsicum plant extract are traditionally used to cure Bronchitis. It is caused by Haemophilus influenzae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Apigenin can effectively deactivate the Shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism

Buddleja asiatica Derived Phytochemicals against Diarrhea

Plants produce nonnutritive compounds that are often extracted to make herbal medicines. It has been reported that extracts of Buddleja asiatica are effective to treat diarrhea. One of the causes ofDiarrhea is an infection by Campylobacter jejuni. The objective of the study is to identify the phytochemical of Buddleja asiatica capable of curing Diarrhea. ATP-phosphoribosyl transferase enzyme plays an important role in Purine Metabolism. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Lignoceric acid can effectively deactivate the transferase enzyme thereby interrupting the life cycle of the organism

Boswellia serrata Derived Phytochemicals against Dysentery

Dysentery is an intestinal inflammation, primarily of the colon. Nature is a major source of medicines for different diseases like Dysentery. Phytochemicals from Boswellia serrata plant extract can cure Dysentery. This objective of the study is to identify the phytochemical of Boswellia serrata capable of curing Dysentery. Molecular docking method applied using “Biovia DiscoveryStudio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that p-cymene can effectively deactivate the enzyme, thereby interrupting the life cycle of the organism

Alpinia galanga Derived Phytochemicals against Shikimate Dehydrogenase Causing Peptic Ulcer

Phytochemicals can be derived from different parts of plants. Different medicinal plants and their phytoextracts have shown anti-microbial action. These medicinal plants play a key role in human health care. Phytochemicals from Alpinia galanga plant extract are traditionally used to cure PepticUlcer. The objective of the study is to identify the phytochemical of Alpinia galanga capable of curing Peptic Ulcer. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Alpinia galanga derived Phytochemicals cannot act effectively against Peptic Ulcer caused by Helicobacter pylori.